Background: , nurses lack the expertise and awareness of enteral nutrition, indicating the necessity of educating them on the nutitonal support . Enhancing the intensive care nurses' knowledge about  nutrition may lead to improved nursing practices. Objectives:  to determine the effectiveness of the   interventional program on nurses practices toward enteral nutritional support for unconscious patient. Methods: A quasi-experimental was conducted at the Critical Care Unit in Imam AL-Hussein Medical City in Holy Karbala  .  A non-probability "purposive sample" of (60) nurses who are working at critical care unit . the sample  divided into two groups, control group consist of (30) nurses and study group consist of (30) nurses exposed to the nursing educational program.  Data were collected by the researcher observed and checked for correct and incorrect performance.  The nurses' Practices check list was composed of (48 ) items. Results: The study's findings indicate that the study group's  practices  of enteral   nutrition support for unconscious patients is greater to that of the control group at the post-test, as compared to the control group's knowledge, so the interventional program was effective in increasing nurses' practices. Conclusion: The nurse's   practice's toward nutrition support  for  unconscious patients is inadequate at pre-test.