The article presents an analysis of the negative impact of noise on the health of machine operators at primary cotton processing plants. The causes of industrial noise in the production shops of cotton ginning enterprises are studied. Permissible noise levels in the workplace are identified in order to eliminate them as much as possible and improve the working conditions of workers. The consequences of vibration exposure to workers and the nature of the violation of physiological functions of the body are determined. The issues of the impact of vibrations on technogenic processes (stability, seismic resistance, service life, etc.) occurring in the production buildings of cotton industry enterprises are considered.