Leadership is the working component of any organization; it's the nerve cell for organizations to exist, function, progress, and flourish by utilizing human and material resources wisely and effectively. Hence, the study of leadership, particularly, in the healthcare sector is very important to bring about quality service delivery both in private and public sectors. The 21st century is characterized by a high pace of changes in technology, social, economic and political, and that healthcare leaders will have a tremendous impact on the lives of many people around the globe, if they possess the technical and functional competences of leadership styles. Leaders at all levels of a healthcare culture can learn the timeless and inevitable lessons through participating stakeholders to have their voices on the critical healthcare issues. The purpose of the review is to explore and highlight the importance of leadership in healthcare organizations. Throughout the review, the authors have learnt that a genuine healthcare leadership bypasses old practices and involves everyone. The study discovers that the complexities, challenges and barriers of healthcare industry are inherent and inevitable, but through thorough and further leadership study in the field, they can be somehow understood, minimized and be used as steppingstones.